Research
Journal publications
References last updated on 2024-03-15 18:38:44
2024
Walsh CG, Ripperger MA, Hu Y, Sheu Y, Lee H, Wilimitis D, Zheutlin AB, Rocha D, Choi KW, Castro VM, Kirchner HL, Chabris CF, Davis LK, Smoller JW (2024). “Development and multi-site external validation of a generalizable risk prediction model for bipolar disorder.” Transl. Psychiatry, 14(1), 58. ISSN 2158-3188, 10.1038/s41398-023-02720-y.
Park H, Wang TD, Wattanasin N, Castro V, Gainer V, Murphy SN (2024). “HistoriView: Implementation and Evaluation of a Novel Approach to Review a Patient Using a Scalable Space-Efficient Timeline without Zoom Interactions.” Appl. Clin. Inform.. ISSN 1869-0327, 10.1055/a-2269-0995.
Bentley KH, Madsen EM, Song E, Zhou Y, Castro V, Lee H, Lee YH, Smoller JW (2024). “Determining Distinct Suicide Attempts From Recurrent Electronic Health Record Codes: Classification Study.” JMIR Form Res, 8, e46364. ISSN 2561-326X, 10.2196/46364.2023
Edlow AG, Castro VM, Shook LL, Haneuse S, Kaimal AJ, Perlis RH (2023). “Sex-Specific Neurodevelopmental Outcomes Among Offspring of Mothers With SARS-CoV-2 Infection During Pregnancy.” JAMA Netw Open, 6(3), e234415. ISSN 2574-3805, 10.1001/jamanetworkopen.2023.4415.
Kessler RC, Bauer MS, Bishop TM, Bossarte RM, Castro VM, Demler OV, Gildea SM, Goulet JL, King AJ, Kennedy CJ, Landes SJ, Liu H, Luedtke A, Mair P, Marx BP, Nock MK, Petukhova MV, Pigeon WR, Sampson NA, Smoller JW, Miller A, Haas G, Benware J, Bradley J, Owen RR, House S, Urosevic S, Weinstock LM (2023). “Evaluation of a model to target high-risk psychiatric inpatients for an intensive postdischarge suicide prevention intervention.” JAMA Psychiatry. ISSN 2168-622X, 2168-6238, 10.1001/jamapsychiatry.2022.4634.
Kessler RC, Bauer MS, Bishop TM, Bossarte RM, Castro VM, Demler OV, Gildea SM, Goulet JL, King AJ, Kennedy CJ, Landes SJ, Liu H, Luedtke A, Mair P, Marx BP, Nock MK, Petukhova MV, Pigeon WR, Sampson NA, Smoller JW, Miller A, Haas G, Benware J, Bradley J, Owen RR, House S, Urosevic S, Weinstock LM (2023). “Evaluation of a Model to Target High-risk Psychiatric Inpatients for an Intensive Postdischarge Suicide Prevention Intervention.” JAMA Psychiatry, 80(3), 230-240. ISSN 2168-622X, 2168-6238, 10.1001/jamapsychiatry.2022.4634.
Sheu Y, Sun J, Lee H, Castro VM, Barak-Corren Y, Song E, Madsen EM, Gordon WJ, Kohane IS, Churchill SE, Reis BY, Cai T, Smoller JW (2023). “An efficient landmark model for prediction of suicide attempts in multiple clinical settings.” Psychiatry Res., 323, 115175. ISSN 0165-1781, 1872-7123, 10.1016/j.psychres.2023.115175.
Pacheco JA, Rasmussen LV, Wiley Jr K, Person TN, Cronkite DJ, Sohn S, Murphy S, Gundelach JH, Gainer V, Castro VM, Liu C, Mentch F, Lingren T, Sundaresan AS, Eickelberg G, Willis V, Furmanchuk A, Patel R, Carrell DS, Deng Y, Walton N, Satterfield BA, Kullo IJ, Dikilitas O, Smith JC, Peterson JF, Shang N, Kiryluk K, Ni Y, Li Y, Nadkarni GN, Rosenthal EA, Walunas TL, Williams MS, Karlson EW, Linder JE, Luo Y, Weng C, Wei W (2023). “Evaluation of the portability of computable phenotypes with natural language processing in the eMERGE network.” Sci. Rep., 13(1), 1971. ISSN 2045-2322, 10.1038/s41598-023-27481-y.
Shook L, Castro V, Herzberg EM, Fourman LT, Kaimal A, Perlis R, Edlow A (2023). “Offspring cardiometabolic outcomes and postnatal growth trajectories after exposure to maternal SARS-CoV-2 infection.” Obesity. ISSN 1930-7381, 10.1101/2023.08.16.23294170.
Barak-Corren Y, Castro VM, Javitt S, Nock MK, Smoller JW, Reis BY (2023). “Improving risk prediction for target subpopulations: Predicting suicidal behaviors among multiple sclerosis patients.” PLoS One, 18(2), e0277483. ISSN 1932-6203, 10.1371/journal.pone.0277483.2022
Nock MK, Millner AJ, Ross EL, Kennedy CJ, Al-Suwaidi M, Barak-Corren Y, Castro VM, Castro-Ramirez F, Lauricella T, Murman N, Petukhova M, Bird SA, Reis B, Smoller JW, Kessler RC (2022). “Prediction of Suicide Attempts Using Clinician Assessment, Patient Self-report, and Electronic Health Records.” JAMA Netw Open, 5(1), e2144373. ISSN 2574-3805, 10.1001/jamanetworkopen.2021.44373.
Edlow AG, Castro VM, Shook LL, Kaimal AJ, Perlis RH (2022). “Neurodevelopmental Outcomes at 1 Year in Infants of Mothers Who Tested Positive for SARS-CoV-2 During Pregnancy.” JAMA Netw Open, 5(6), e2215787. ISSN 2574-3805, 10.1001/jamanetworkopen.2022.15787.
Han L, Wang X, Cai T (2022). “Identifying surrogate markers in real-world comparative effectiveness research.” Stat. Med., 41(26), 5290-5304. ISSN 0277-6715, 1097-0258, 10.1002/sim.9569.
Castro VM, Hart KL, Sacks CA, Murphy SN, Perlis RH, McCoy Jr TH (2022). “Longitudinal validation of an electronic health record delirium prediction model applied at admission in COVID-19 patients.” Gen. Hosp. Psychiatry, 74, 9-17. ISSN 0163-8343, 1873-7714, 10.1016/j.genhosppsych.2021.10.005.
Zhou D, Gan Z, Shi X, Patwari A, Rush E, Bonzel C, Panickan VA, Hong C, Ho Y, Cai T, Costa L, Li X, Castro VM, Murphy SN, Brat G, Weber G, Avillach P, Gaziano JM, Cho K, Liao KP, Lu J, Cai T (2022). “Multiview Incomplete Knowledge Graph Integration with application to cross-institutional EHR data harmonization.” J. Biomed. Inform., 133, 104147. ISSN 1532-0464, 1532-0480, 10.1016/j.jbi.2022.104147.
Castro VM, Rosand J, Giacino JT, McCoy TH, Perlis RH (2022). “Case-control study of neuropsychiatric symptoms in electronic health records following COVID-19 hospitalization in 2 academic health systems.” Mol. Psychiatry. ISSN 1359-4184, 1476-5578, 10.1038/s41380-022-01646-z.
Bayramli I, Castro V, Barak-Corren Y, Madsen EM, Nock MK, Smoller JW, Reis BY (2022). “Predictive structured-unstructured interactions in EHR models: A case study of suicide prediction.” NPJ Digit. Med., 5(1), 15. ISSN 2398-6352, 10.1038/s41746-022-00558-0.
Park H, Wang TD, Wattanasin N, Castro VM, Gainer V, Goryachev S, Murphy S (2022). “The Digital Analytic Patient Reviewer (DAPR) for COVID-19 Data Mart Validation.” Methods Inf. Med.. ISSN 0026-1270, 2511-705X, 10.1055/a-1938-0436.
Pfaff ER, Girvin AT, Gabriel DL, Kostka K, Morris M, Palchuk MB, Lehmann HP, Amor B, Bissell M, Bradwell KR, Gold S, Hong SS, Loomba J, Manna A, McMurry JA, Niehaus E, Qureshi N, Walden A, Zhang XT, Zhu RL, Moffitt RA, Haendel MA, Chute CG, N3C Consortium, Adams WG, Al-Shukri S, Anzalone A, Baghal A, Bennett TD, Bernstam EV, Bernstam EV, Bissell MM, Bush B, Campion TR, Castro V, Chang J, Chaudhari DD, Chen W, Chu S, Cimino JJ, Crandall KA, Crooks M, Davies SJD, DiPalazzo J, Dorr D, Eckrich D, Eltinge SE, Fort DG, Golovko G, Gupta S, Haendel MA, Hajagos JG, Hanauer DA, Harnett BM, Horswell R, Huang N, Johnson SG, Kahn M, Khanipov K, Kieler C, Luzuriaga KRD, Maidlow S, Martinez A, Mathew J, McClay JC, McMahan G, Melancon B, Meystre S, Miele L, Morizono H, Pablo R, Patel L, Phuong J, Popham DJ, Pulgarin C, Santos C, Sarkar IN, Sazo N, Setoguchi S, Soby S, Surampalli S, Suver C, Vangala UMR, Visweswaran S, Oehsen Jv, Walters KM, Wiley L, Williams DA, Zai A (2022). “Synergies between centralized and federated approaches to data quality: a report from the national COVID cohort collaborative.” J. Am. Med. Inform. Assoc., 29(4), 609-618. ISSN 1067-5027, 1527-974X, 10.1093/jamia/ocab217.
Bentley KH, Zuromski KL, Fortgang RG, Madsen EM, Kessler D, Lee H, Nock MK, Reis BY, Castro VM, Smoller JW (2022). “Implementing Machine Learning Models for Suicide Risk Prediction in Clinical Practice: Focus Group Study With Hospital Providers.” JMIR Form Res, 6(3), e30946. ISSN 2561-326X, 10.2196/30946.2021
Castro VM, McCoy TH, Perlis RH (2021). “Assessment of the Performance Consistency of an Adverse Outcome Prediction Tool for Patients Hospitalized With COVID-19.” JAMA Netw Open, 4(7), e2118413. ISSN 2574-3805, 10.1001/jamanetworkopen.2021.18413.
McCoy Jr TH, Castro VM, Hart KL, Perlis RH (2021). “Stratified delirium risk using prescription medication data in a state-wide cohort.” Gen. Hosp. Psychiatry, 71, 114-120. ISSN 0163-8343, 1873-7714, 10.1016/j.genhosppsych.2021.05.001.
Castro VM, Sacks CA, Perlis RH, McCoy TH (2021). “Development and External Validation of a Delirium Prediction Model for Hospitalized Patients With Coronavirus Disease 2019.” J Acad Consult Liaison Psychiatry. ISSN 2667-2960, 10.1016/j.jaclp.2020.12.005.
Zhang J, Can A, Lai PMR, Mukundan S, Castro VM, Dligach D, Finan S, Gainer VS, Shadick NA, Savova G, Murphy SN, Cai T, Weiss ST, Du R (2021). “Geometric Features Associated with Middle Cerebral Artery Bifurcation Aneurysm Formation: A Matched Case-Control Study.” J. Stroke Cerebrovasc. Dis., 31(3), 106268. ISSN 1052-3057, 1532-8511, 10.1016/j.jstrokecerebrovasdis.2021.106268.
Zhang J, Can A, Lai PMR, Mukundan Jr S, Castro VM, Dligach D, Finan S, Gainer VS, Shadick NA, Savova G, Murphy SN, Cai T, Weiss ST, Du R (2021). “Vascular Geometry Associated with Anterior Communicating Artery Aneurysm Formation.” World Neurosurg., 146, e1318-e1325. ISSN 1878-8750, 1878-8769, 10.1016/j.wneu.2020.11.160.
Morley TJ, Han L, Castro VM, Morra J, Perlis RH, Cox NJ, Bastarache L, Ruderfer DM (2021). “Phenotypic signatures in clinical data enable systematic identification of patients for genetic testing.” Nat. Med.. ISSN 1078-8956, 1546-170X, 10.1038/s41591-021-01356-z.
Zhang J, Can A, Lai PMR, Mukundan Jr S, Castro VM, Dligach D, Finan S, Gainer VS, Shadick NA, Savova G, Murphy SN, Cai T, Weiss ST, Du R (2021). “Morphological variables associated with ruptured basilar tip aneurysms.” Sci. Rep., 11(1), 2526. ISSN 2045-2322, 10.1038/s41598-021-81364-8.
Zhang J, Lai PMR, Can A, Mukundan S, Castro VM, Dligach D, Finan S, Gainer VS, Shadick NA, Savova G, Murphy SN, Cai T, Weiss ST, Du R (2021). “Tobacco use and age are associated with different morphologic features of anterior communicating artery aneurysms.” Sci. Rep., 11(1), 4791. ISSN 2045-2322, 10.1038/s41598-021-84315-5.
Hong C, Rush E, Liu M, Zhou D, Sun J, Sonabend A, Castro VM, Schubert P, Panickan VA, Cai T, Costa L, He Z, Link N, Hauser R, Gaziano JM, Murphy SN, Ostrouchov G, Ho Y, Begoli E, Lu J, Cho K, Liao KP, Cai T, VA Million Veteran Program (2021). “Clinical knowledge extraction via sparse embedding regression (KESER) with multi-center large scale electronic health record data.” NPJ Digit Med, 4(1), 151. ISSN 2398-6352, 10.1038/s41746-021-00519-z.
Klann JG, Weber GM, Estiri H, Moal B, Avillach P, Hong C, Castro V, Maulhardt T, Tan ALM, Geva A, Beaulieu-Jones BK, Malovini A, South AM, Visweswaran S, Omenn GS, Ngiam KY, Mandl KD, Boeker M, Olson KL, Mowery DL, Morris M, Follett RW, Hanauer DA, Bellazzi R, Moore JH, Loh NW, Bell DS, Wagholikar KB, Chiovato L, Tibollo V, Rieg S, Li ALLJ, Jouhet V, Schriver E, Samayamuthu MJ, Xia Z, Hutch M, Luo Y, Consortium for Clinical Characterization of COVID-19 by EHR (4CE) (CONSORTIA AUTHOR), Kohane IS, Brat GA, Murphy SN (2021). “Validation of an Internationally Derived Patient Severity Phenotype to Support COVID-19 Analytics from Electronic Health Record Data.” J. Am. Med. Inform. Assoc.. ISSN 1067-5027, 1527-974X, 10.1093/jamia/ocab018.
Bayramli I, Castro V, Barak-Corren Y, Madsen EM, Nock MK, Smoller JW, Reis BY (2021). “Temporally informed random forests for suicide risk prediction.” J. Am. Med. Inform. Assoc., 29(1), 62-71. ISSN 1067-5027, 1527-974X, 10.1093/jamia/ocab225.
Castro VM, Gainer V, Wattanasin N, Benoit B, Cagan A, Ghosh B, Goryachev S, Metta R, Park H, Wang D, Mendis M, Rees M, Herrick C, Murphy SN (2021). “The Mass General Brigham Biobank Portal: an i2b2-based data repository linking disparate and high-dimensional patient data to support multimodal analytics.” J. Am. Med. Inform. Assoc.. ISSN 1067-5027, 1527-974X, 10.1093/jamia/ocab264.
Zhang J, Can A, Lai PMR, Mukundan Jr S, Castro VM, Dligach D, Finan S, Gainer V, Shadick N, Savova G, Murphy SN, Cai T, Weiss ST, Du R (2021). “Geometric variations associated with posterior communicating artery aneurysms.” J. Neurointerv. Surg.. ISSN 1759-8478, 1759-8486, 10.1136/neurintsurg-2020-017062.
Castro VM, Gunning FM, McCoy TH, Perlis RH (2021). “Mood Disorders and Outcomes of COVID-19 Hospitalizations.” Am. J. Psychiatry, 178(6), 541-547. ISSN 0002-953X, 1535-7228, 10.1176/appi.ajp.2020.20060842.2020
Castro VM, Perlis RH (2020). “Electronic Health Record Documentation of Psychiatric Assessments in Massachusetts Emergency Department and Outpatient Settings During the Coronavirus Disease 2019 (COVID-19) Pandemic.” JAMA Netw Open, 3(6), e2011346. ISSN 2574-3805, 10.1001/jamanetworkopen.2020.11346.
Barak-Corren Y, Castro VM, Nock MK, Mandl KD, Madsen EM, Seiger A, Adams WG, Applegate RJ, Bernstam EV, Klann JG, McCarthy EP, Murphy SN, Natter M, Ostasiewski B, Patibandla N, Rosenthal GE, Silva GS, Wei K, Weber GM, Weiler SR, Reis BY, Smoller JW (2020). “Validation of an Electronic Health Record-Based Suicide Risk Prediction Modeling Approach Across Multiple Health Care Systems.” JAMA Netw Open, 3(3), e201262. ISSN 2574-3805, 10.1001/jamanetworkopen.2020.1262.
Castro VM, McCoy TH, Perlis RH (2020). “Laboratory Findings Associated With Severe Illness and Mortality Among Hospitalized Individuals With Coronavirus Disease 2019 in Eastern Massachusetts.” JAMA Netw Open, 3(10), e2023934. ISSN 2574-3805, 10.1001/jamanetworkopen.2020.23934.
Estiri H, Strasser ZH, Klann JG, McCoy TH, Wagholikar KB, Vasey S, Castro VM, Murphy ME, Murphy SN (2020). “Transitive Sequencing Medical Records for Mining Predictive and Interpretable Temporal Representations.” Patterns Prejudice, 1(4), 100051. ISSN 0031-322X, 2666-3899, 10.1016/j.patter.2020.100051.
Zhang J, Can A, Lai PMR, Mukundan Jr S, Castro VM, Dligach D, Finan S, Yu S, Gainer VS, Shadick NA, Savova G, Murphy SN, Cai T, Weiss ST, Du R (2020). “Age and morphology of posterior communicating artery aneurysms.” Sci. Rep., 10(1), 11545. ISSN 2045-2322, 10.1038/s41598-020-68276-9.
Zhang J, Can A, Lai PMR, Mukundan Jr S, Castro VM, Dligach D, Finan S, Gainer VS, Shadick NA, Savova G, Murphy SN, Cai T, Weiss ST, Du R (2020). “Surrounding vascular geometry associated with basilar tip aneurysm formation.” Sci. Rep., 10(1), 17928. ISSN 2045-2322, 10.1038/s41598-020-74266-8.
Ahuja Y, Zhou D, He Z, Sun J, Castro VM, Gainer V, Murphy SN, Hong C, Cai T (2020). “sureLDA: A multidisease automated phenotyping method for the electronic health record.” J. Am. Med. Inform. Assoc., 27(8), 1235-1243. ISSN 1067-5027, 1527-974X, 10.1093/jamia/ocaa079.
Castro VM, Ross RA, McBride SM, Perlis RH (2020). “Identifying common pharmacotherapies associated with reduced COVID-19 morbidity using electronic health records.” MedRxiv. 10.1101/2020.04.11.20061994.2019
Skaljic M, Patel IH, Pellegrini AM, Castro VM, Perlis RH, Gordon DD (2019). “Prevalence of Financial Considerations Documented in Primary Care Encounters as Identified by Natural Language Processing Methods.” JAMA Netw Open, 2(8), e1910399. ISSN 2574-3805, 10.1001/jamanetworkopen.2019.10399.
eMERGE Consortium. Electronic address: agibbs@bcm.edu, eMERGE Consortium (2019). “Harmonizing Clinical Sequencing and Interpretation for the eMERGE III Network.” Am. J. Hum. Genet., 105(3), 588-605. ISSN 0002-9297, 1537-6605, 10.1016/j.ajhg.2019.07.018.
Jorge A, Castro VM, Barnado A, Gainer V, Hong C, Cai T, Cai T, Carroll R, Denny JC, Crofford L, Costenbader KH, Liao KP, Karlson EW, Feldman CH (2019). “Identifying lupus patients in electronic health records: Development and validation of machine learning algorithms and application of rule-based algorithms.” Semin. Arthritis Rheum., 49(1), 84-90. ISSN 0049-0172, 1532-866X, 10.1016/j.semarthrit.2019.01.002.
Zhang Y, Cai T, Yu S, Cho K, Hong C, Sun J, Huang J, Ho Y, Ananthakrishnan AN, Xia Z, Shaw SY, Gainer V, Castro V, Link N, Honerlaw J, Huang S, Gagnon D, Karlson EW, Plenge RM, Szolovits P, Savova G, Churchill S, O’Donnell C, Murphy SN, Gaziano JM, Kohane I, Cai T, Liao KP (2019). “High-throughput phenotyping with electronic medical record data using a common semi-supervised approach (PheCAP).” Nat. Protoc., 14(12), 3426-3444. ISSN 1754-2189, 1750-2799, 10.1038/s41596-019-0227-6.
Can A, Lai PMR, Castro VM, Yu S, Dligach D, Finan S, Gainer V, Shadick NA, Savova G, Murphy S, Cai T, Weiss ST, Du R (2019). “Decreased Total Iron Binding Capacity May Correlate with Ruptured Intracranial Aneurysms.” Sci. Rep., 9(1), 6054. ISSN 2045-2322, 10.1038/s41598-019-42622-y.
Moran LV, Ongur D, Hsu J, Castro VM, Perlis RH, Schneeweiss S (2019). “Psychosis with Methylphenidate or Amphetamine in Patients with ADHD.” N. Engl. J. Med., 380(12), 1128-1138. ISSN 0028-4793, 1533-4406, 10.1056/NEJMoa1813751.
Liao KP, Sun J, Cai TA, Link N, Hong C, Huang J, Huffman JE, Gronsbell J, Zhang Y, Ho Y, Castro V, Gainer V, Murphy SN, O’Donnell CJ, Gaziano JM, Cho K, Szolovits P, Kohane IS, Yu S, Cai T (2019). “High-throughput multimodal automated phenotyping (MAP) with application to PheWAS.” J. Am. Med. Inform. Assoc., 26(11), 1255-1262. ISSN 1067-5027, 1527-974X, 10.1093/jamia/ocz066.
Zhang J, Can A, Mukundan S, Steigner M, Castro VM, Dligach D, Finan S, Yu S, Gainer V, Shadick NA, Savova G, Murphy S, Cai T, Wang Z, Weiss ST, Du R (2019). “Morphological Variables Associated With Ruptured Middle Cerebral Artery Aneurysms.” Neurosurgery, 85(1), 75-83. ISSN 0148-396X, 1524-4040, 10.1093/neuros/nyy213.
Zheutlin AB, Dennis J, Karlsson Linnér R, Moscati A, Restrepo N, Straub P, Ruderfer D, Castro VM, Chen C, Ge T, Huckins LM, Charney A, Kirchner HL, Stahl EA, Chabris CF, Davis LK, Smoller JW (2019). “Penetrance and Pleiotropy of Polygenic Risk Scores for Schizophrenia in 106,160 Patients Across Four Health Care Systems.” Am. J. Psychiatry, 176(10), 846-855. ISSN 0002-953X, 1535-7228, 10.1176/appi.ajp.2019.18091085.2018
Can A, Castro VM, Ozdemir YH, Dagen S, Dligach D, Finan S, Yu S, Gainer V, Shadick NA, Savova G, Murphy S, Cai T, Weiss ST, Du R (2018). “Alcohol Consumption and Aneurysmal Subarachnoid Hemorrhage.” Transl. Stroke Res., 9(1), 13-19. ISSN 1868-4483, 1868-601X, 10.1007/s12975-017-0557-z.
Can A, Castro VM, Ozdemir YH, Dagen S, Dligach D, Finan S, Yu S, Gainer V, Shadick NA, Savova G, Murphy S, Cai T, Weiss ST, Du R (2018). “Heroin Use Is Associated with Ruptured Saccular Aneurysms.” Transl. Stroke Res., 9(4), 340-346. ISSN 1868-4483, 1868-601X, 10.1007/s12975-017-0582-y.
McCoy Jr TH, Castro VM, Hart KL, Pellegrini AM, Yu S, Cai T, Perlis RH (2018). “Genome-wide Association Study of Dimensional Psychopathology Using Electronic Health Records.” Biol. Psychiatry, 83(12), 1005-1011. ISSN 0006-3223, 1873-2402, 10.1016/j.biopsych.2017.12.004.
McCoy Jr TH, Yu S, Hart KL, Castro VM, Brown HE, Rosenquist JN, Doyle AE, Vuijk PJ, Cai T, Perlis RH (2018). “High Throughput Phenotyping for Dimensional Psychopathology in Electronic Health Records.” Biol. Psychiatry, 83(12), 997-1004. ISSN 0006-3223, 1873-2402, 10.1016/j.biopsych.2018.01.011.
Chen C, Lee PH, Castro VM, Minnier J, Charney AW, Stahl EA, Ruderfer DM, Murphy SN, Gainer V, Cai T, Jones I, Pato CN, Pato MT, Landén M, Sklar P, Perlis RH, Smoller JW (2018). “Genetic validation of bipolar disorder identified by automated phenotyping using electronic health records.” Transl. Psychiatry, 8(1), 86. ISSN 2158-3188, 10.1038/s41398-018-0133-7.
McCoy TH, Castro VM, Cagan A, Snapper L, Roberson A, Perlis RH (2018). “Cytochrome P450 interactions are common and consequential in Massachusetts hospital discharges.” Pharmacogenomics J., 18(2), 347-350. ISSN 1470-269X, 1473-1150, 10.1038/tpj.2017.30.
Can A, Castro VM, Yu S, Dligach D, Finan S, Gainer VS, Shadick NA, Savova G, Murphy S, Cai T, Weiss ST, Du R (2018). “Antihyperglycemic Agents Are Inversely Associated With Intracranial Aneurysm Rupture.” Stroke, 49(1), 34-39. ISSN 0039-2499, 1524-4628, 10.1161/STROKEAHA.117.019249.
Can A, Castro VM, Dligach D, Finan S, Yu S, Gainer V, Shadick NA, Savova G, Murphy S, Cai T, Weiss ST, Du R (2018). “Lipid-Lowering Agents and High HDL (High-Density Lipoprotein) Are Inversely Associated With Intracranial Aneurysm Rupture.” Stroke, 49(5), 1148-1154. ISSN 0039-2499, 1524-4628, 10.1161/STROKEAHA.117.019972.
Can A, Rudy RF, Castro VM, Dligach D, Finan S, Yu S, Gainer V, Shadick NA, Savova G, Murphy S, Cai T, Weiss ST, Du R (2018). “Low Serum Calcium and Magnesium Levels and Rupture of Intracranial Aneurysms.” Stroke, 49(7), 1747-1750. ISSN 0039-2499, 1524-4628, 10.1161/STROKEAHA.118.020963.
Can A, Castro VM, Dligach D, Finan S, Yu S, Gainer V, Shadick NA, Savova G, Murphy S, Cai T, Weiss ST, Du R (2018). “Elevated International Normalized Ratio Is Associated With Ruptured Aneurysms.” Stroke, 49(9), 2046-2052. ISSN 0039-2499, 1524-4628, 10.1161/STROKEAHA.118.022412.
Can A, Rudy RF, Castro VM, Yu S, Dligach D, Finan S, Gainer V, Shadick NA, Savova G, Murphy S, Cai T, Weiss ST, Du R (2018). “Association between aspirin dose and subarachnoid hemorrhage from saccular aneurysms: A case-control study.” Neurology, 91(12), e1175-e1181. ISSN 0028-3878, 1526-632X, 10.1212/WNL.0000000000006200.2017
Ou Y, Zöllei L, Retzepi K, Castro V, Bates SV, Pieper S, Andriole KP, Murphy SN, Gollub RL, Grant PE (2017). “Using clinically acquired MRI to construct age-specific ADC atlases: Quantifying spatiotemporal ADC changes from birth to 6-year old.” Hum. Brain Mapp., 38(6), 3052-3068. ISSN 1065-9471, 1097-0193, 10.1002/hbm.23573.
Venkatesh KK, Castro VM, Perlis RH, Kaimal AJ (2017). “815: Impact of antidepressant treatment during pregnancy on obstetric outcomes among women previously treated for depression.” Am. J. Obstet. Gynecol., 216(1), S466-S467. ISSN 0002-9378, 1097-6868, 10.1016/j.ajog.2016.11.1056.
Venkatesh KK, Kaimal AJ, Castro VM, Perlis RH (2017). “Improving discrimination in antepartum depression screening using the Edinburgh Postnatal Depression Scale.” J. Affect. Disord., 214, 1-7. ISSN 0165-0327, 1573-2517, 10.1016/j.jad.2017.01.042.
Venkatesh KK, Castro VM, Perlis RH, Kaimal AJ (2017). “Impact of antidepressant treatment during pregnancy on obstetric outcomes among women previously treated for depression: an observational cohort study.” J. Perinatol., 37(9), 1003-1009. ISSN 0743-8346, 1476-5543, 10.1038/jp.2017.92.
Song J, Bergen SE, Di Florio A, Karlsson R, Charney A, Ruderfer DM, Stahl EA, Members of the International Cohort Collection for Bipolar Disorder (ICCBD), Chambert KD, Moran JL, Gordon-Smith K, Forty L, Green EK, Jones I, Jones L, Scolnick EM, Sklar P, Smoller JW, Lichtenstein P, Hultman C, Craddock N, Landén M (2017). “Genome-wide association study identifies SESTD1 as a novel risk gene for lithium-responsive bipolar disorder.” Mol. Psychiatry, 22(8), 1223. ISSN 1359-4184, 1476-5578, 10.1038/mp.2016.246.
McCoy TH, Castro VM, Snapper L, Hart K, Januzzi JL, Huffman JC, Perlis RH (2017). “Polygenic loading for major depression is associated with specific medical comorbidity.” Transl. Psychiatry, 7(9), e1238. ISSN 2158-3188, 10.1038/tp.2017.201.
McCoy TH, Castro VM, Cagan A, Roberson AM, Perlis RH (2017). “Prevalence and implications of cytochrome P450 substrates in Massachusetts hospital discharges.” Pharmacogenomics J., 17(4), 382-385. ISSN 1470-269X, 1473-1150, 10.1038/tpj.2016.24.
McCoy Jr TH, Castro VM, Cagan A, Roberson AM, Perlis RH (2017). “Validation of a risk stratification tool for fall-related injury in a state-wide cohort.” BMJ Open, 7(2), e012189. ISSN 2044-6055, 10.1136/bmjopen-2016-012189.
Rosenberg MA, Lubitz SA, Lin H, Kosova G, Castro VM, Huang P, Ellinor PT, Perlis RH, Newton-Cheh C (2017). “Validation of Polygenic Scores for QT Interval in Clinical Populations.” Circ. Cardiovasc. Genet., 10(5). ISSN 1942-325X, 1942-3268, 10.1161/CIRCGENETICS.117.001724.
Barak-Corren Y, Castro VM, Javitt S, Hoffnagle AG, Dai Y, Perlis RH, Nock MK, Smoller JW, Reis BY (2017). “Predicting Suicidal Behavior From Longitudinal Electronic Health Records.” Am. J. Psychiatry, 174(2), 154-162. ISSN 0002-953X, 1535-7228, 10.1176/appi.ajp.2016.16010077.
Castro VM, Dligach D, Finan S, Yu S, Can A, Abd-El-Barr M, Gainer V, Shadick NA, Murphy S, Cai T, Savova G, Weiss ST, Du R (2017). “Large-scale identification of patients with cerebral aneurysms using natural language processing.” Neurology, 88(2), 164-168. ISSN 0028-3878, 1526-632X, 10.1212/WNL.0000000000003490.
Can A, Castro VM, Ozdemir YH, Dagen S, Yu S, Dligach D, Finan S, Gainer V, Shadick NA, Murphy S, Cai T, Savova G, Dammers R, Weiss ST, Du R (2017). “Association of intracranial aneurysm rupture with smoking duration, intensity, and cessation.” Neurology, 89(13), 1408-1415. ISSN 0028-3878, 1526-632X, 10.1212/WNL.0000000000004419.
Murphy S, Castro V, Mandl K (2017). “Grappling with the Future Use of Big Data for Translational Medicine and Clinical Care.” Yearb. Med. Inform., 26(1), 96-102. ISSN 0943-4747, 2364-0502, 10.15265/IY-2017-020.
McCoy TH, Castro VM, Snapper LA, Hart KL, Perlis RH (2017). “Efficient genome-wide association in biobanks using topic modeling identifies multiple novel disease loci.” Mol. Med., 23, 285-294. ISSN 1076-1551, 1528-3658, 10.2119/molmed.2017.00100.2016
McCoy Jr TH, Castro VM, Roberson AM, Snapper LA, Perlis RH (2016). “Improving Prediction of Suicide and Accidental Death After Discharge From General Hospitals With Natural Language Processing.” JAMA Psychiatry, 73(10), 1064-1071. ISSN 2168-622X, 2168-6238, 10.1001/jamapsychiatry.2016.2172.
Castro VM, Roberson AM, McCoy TH, Wiste A, Cagan A, Smoller JW, Rosenbaum JF, Ostacher M, Perlis RH (2016). “Stratifying Risk for Renal Insufficiency Among Lithium-Treated Patients: An Electronic Health Record Study.” Neuropsychopharmacology, 41(4), 1138-1143. ISSN 0893-133X, 1740-634X, 10.1038/npp.2015.254.
Rumshisky A, Ghassemi M, Naumann T, Szolovits P, Castro VM, McCoy TH, Perlis RH (2016). “Predicting early psychiatric readmission with natural language processing of narrative discharge summaries.” Transl. Psychiatry, 6(10), e921. ISSN 2158-3188, 10.1038/tp.2015.182.
Castro VM, Kong SW, Clements CC, Brady R, Kaimal AJ, Doyle AE, Robinson EB, Churchill SE, Kohane IS, Perlis RH (2016). “Absence of evidence for increase in risk for autism or attention-deficit hyperactivity disorder following antidepressant exposure during pregnancy: a replication study.” Transl. Psychiatry, 6, e708. ISSN 2158-3188, 10.1038/tp.2015.190.
Venkatesh KK, Riley L, Castro VM, Perlis RH, Kaimal AJ (2016). “Association of Antenatal Depression Symptoms and Antidepressant Treatment With Preterm Birth.” Obstet. Gynecol., 127(5), 926-933. ISSN 0029-7844, 1873-233X, 10.1097/AOG.0000000000001397.
Balekian DS, Linnemann RW, Castro VM, Perlis R, Thadhani R, Camargo Jr CA (2016). “Pre-birth cohort study of atopic dermatitis and severe bronchiolitis during infancy.” Pediatr. Allergy Immunol., 27(4), 413-418. ISSN 0905-6157, 1399-3038, 10.1111/pai.12532.
Gainer VS, Cagan A, Castro VM, Duey S, Ghosh B, Goodson AP, Goryachev S, Metta R, Wang TD, Wattanasin N, Murphy SN (2016). “The Biobank Portal for Partners Personalized Medicine: A Query Tool for Working with Consented Biobank Samples, Genotypes, and Phenotypes Using i2b2.” J Pers Med, 6(1). ISSN 2075-4426, 10.3390/jpm6010011.
Boutin NT, Mathieu K, Hoffnagle AG, Allen NL, Castro VM, Morash M, O’Rourke PP, Hohmann EL, Herring N, Bry L, Slaugenhaupt SA, Karlson EW, Weiss ST, Smoller JW (2016). “Implementation of Electronic Consent at a Biobank: An Opportunity for Precision Medicine Research.” J Pers Med, 6(2). ISSN 2075-4426, 10.3390/jpm6020017.
Roberson AM, Castro VM, Cagan A, Perlis RH (2016). “Antidepressant nonadherence in routine clinical settings determined from discarded blood samples.” J. Clin. Psychiatry, 77(3), 359-362. ISSN 0160-6689, 1555-2101, 10.4088/JCP.14m09612.2015
Arloth J, Bogdan R, Weber P, Frishman G, Menke A, Wagner KV, Balsevich G, Schmidt MV, Karbalai N, Czamara D, Altmann A, Trümbach D, Wurst W, Mehta D, Uhr M, Klengel T, Erhardt A, Carey CE, Conley ED, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (PGC), Ruepp A, Müller-Myhsok B, Hariri AR, Binder EB, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium PGC (2015). “Genetic Differences in the Immediate Transcriptome Response to Stress Predict Risk-Related Brain Function and Psychiatric Disorders.” Neuron, 86(5), 1189-1202. ISSN 0896-6273, 1097-4199, 10.1016/j.neuron.2015.05.034.
Clements CC, Castro VM, Blumenthal SR, Rosenfield HR, Murphy SN, Fava M, Erb JL, Churchill SE, Kaimal AJ, Doyle AE, Robinson EB, Smoller JW, Kohane IS, Perlis RH (2015). “Prenatal antidepressant exposure is associated with risk for attention-deficit hyperactivity disorder but not autism spectrum disorder in a large health system.” Mol. Psychiatry, 20(6), 727-734. ISSN 1359-4184, 1476-5578, 10.1038/mp.2014.90.
Peyrot WJ, Lee SH, Milaneschi Y, Abdellaoui A, Byrne EM, Esko T, de Geus EJC, Hemani G, Hottenga JJ, Kloiber S, Levinson DF, Lucae S, Major Depressive Disorder Working Group of the Psychiatric GWAS Consortium (Corporate Collaborator), Martin NG, Medland SE, Metspalu A, Milani L, Noethen MM, Potash JB, Rietschel M, Rietveld CA, Ripke S, Shi J, Social Science Genetic Association Consortium Corporate Collaborator, Willemsen G, Zhu Z, Boomsma DI, Wray NR, Penninx BWJH, Major Depressive Disorder Working Group of the Psychiatric GWAS Consortium Corporate Collaborator, Social Science Genetic Association Consortium Corporate Collaborator (2015). “The association between lower educational attainment and depression owing to shared genetic effects? Results in ~25,000 subjects.” Mol. Psychiatry, 20(6), 735-743. ISSN 1359-4184, 1476-5578, 10.1038/mp.2015.50.
Uchida M, Spencer AE, Biederman J, Castro VM, Kenworthy T, Chan J, Rosales AM, Newton-Cheh C, Perlis RH (2015). “A Systematic Evaluation of the QTc Interval and Antidepressants in Youth: An Electronic Health Record Study.” J. Dev. Behav. Pediatr., 36(6), 434-439. ISSN 0196-206X, 1536-7312, 10.1097/DBP.0000000000000188.
Castro VM, Minnier J, Murphy SN, Kohane I, Churchill SE, Gainer V, Cai T, Hoffnagle AG, Dai Y, Block S, Weill SR, Nadal-Vicens M, Pollastri AR, Rosenquist JN, Goryachev S, Ongur D, Sklar P, Perlis RH, Smoller JW, International Cohort Collection for Bipolar Disorder Consortium (2015). “Validation of electronic health record phenotyping of bipolar disorder cases and controls.” Am. J. Psychiatry, 172(4), 363-372. ISSN 0002-953X, 1535-7228, 10.1176/appi.ajp.2014.14030423.
McCoy TH, Castro VM, Rosenfield HR, Cagan A, Kohane IS, Perlis RH (2015). “A clinical perspective on the relevance of research domain criteria in electronic health records.” Am. J. Psychiatry, 172(4), 316-320. ISSN 0002-953X, 1535-7228, 10.1176/appi.ajp.2014.14091177.
Castro V, Shen Y, Yu S, Finan S, Pau CT, Gainer V, Keefe CC, Savova G, Murphy SN, Cai T, Welt CK (2015). “Identification of subjects with polycystic ovary syndrome using electronic health records.” Reprod. Biol. Endocrinol., 13, 116. ISSN 1477-7827, 10.1186/s12958-015-0115-z.
McCoy TH, Castro VM, Cagan A, Roberson AM, Kohane IS, Perlis RH (2015). “Sentiment Measured in Hospital Discharge Notes Is Associated with Readmission and Mortality Risk: An Electronic Health Record Study.” PLoS One, 10(8), e0136341. ISSN 1932-6203, 10.1371/journal.pone.0136341.
Perlis R, McCoy T, Wiste A, Ostacher M, Castro V (2015). “Stratifying risk using large-scale electronic health records data.” Bipolar Disord., 17. ISSN 1398-5647, .2014
Blumenthal SR, Castro VM, Clements CC, Rosenfield HR, Murphy SN, Fava M, Weilburg JB, Erb JL, Churchill SE, Kohane IS, Smoller JW, Perlis RH (2014). “An electronic health records study of long-term weight gain following antidepressant use.” JAMA Psychiatry, 71(8), 889-896. ISSN 2168-622X, 2168-6238, 10.1001/jamapsychiatry.2014.414.
O’Dushlaine C, Ripke S, Ruderfer DM, Hamilton SP, Fava M, Iosifescu DV, Kohane IS, Churchill SE, Castro VM, Clements CC, Blumenthal SR, Murphy SN, Smoller JW, Perlis RH (2014). “Rare copy number variation in treatment-resistant major depressive disorder.” Biol. Psychiatry, 76(7), 536-541. ISSN 0006-3223, 1873-2402, 10.1016/j.biopsych.2013.10.028.
Castro VM, Apperson WK, Gainer VS, Ananthakrishnan AN, Goodson AP, Wang TD, Herrick CD, Murphy SN (2014). “Evaluation of matched control algorithms in EHR-based phenotyping studies: a case study of inflammatory bowel disease comorbidities.” J. Biomed. Inform., 52, 105-111. ISSN 1532-0464, 1532-0480, 10.1016/j.jbi.2014.08.012.
Castro VM, McCoy TH, Cagan A, Rosenfield HR, Murphy SN, Churchill SE, Kohane IS, Perlis RH (2014). “Stratification of risk for hospital admissions for injury related to fall: cohort study.” BMJ, 349, g5863. ISSN 0959-8138, 1756-1833, 10.1136/bmj.g5863.2013
Major Depressive Disorder Working Group of the Psychiatric GWAS Consortium, Ripke S, Wray NR, Lewis CM, Hamilton SP, Weissman MM, Breen G, Byrne EM, Blackwood DHR, Boomsma DI, Cichon S, Heath AC, Holsboer F, Lucae S, Madden PAF, Martin NG, McGuffin P, Muglia P, Noethen MM, Penninx BP, Pergadia ML, Potash JB, Rietschel M, Lin D, Müller-Myhsok B, Shi J, Steinberg S, Grabe HJ, Lichtenstein P, Magnusson P, Perlis RH, Preisig M, Smoller JW, Stefansson K, Uher R, Kutalik Z, Tansey KE, Teumer A, Viktorin A, Barnes MR, Bettecken T, Binder EB, Breuer R, Castro VM, Churchill SE, Coryell WH, Craddock N, Craig IW, Czamara D, De Geus EJ, Degenhardt F, Farmer AE, Fava M, Frank J, Gainer VS, Gallagher PJ, Gordon SD, Goryachev S, Gross M, Guipponi M, Henders AK, Herms S, Hickie IB, Hoefels S, Hoogendijk W, Hottenga JJ, Iosifescu DV, Ising M, Jones I, Jones L, Jung-Ying T, Knowles JA, Kohane IS, Kohli MA, Korszun A, Landen M, Lawson WB, Lewis G, Macintyre D, Maier W, Mattheisen M, McGrath PJ, McIntosh A, McLean A, Middeldorp CM, Middleton L, Montgomery GM, Murphy SN, Nauck M, Nolen WA, Nyholt DR, O’Donovan M, Oskarsson H, Pedersen N, Scheftner WA, Schulz A, Schulze TG, Shyn SI, Sigurdsson E, Slager SL, Smit JH, Stefansson H, Steffens M, Thorgeirsson T, Tozzi F, Treutlein J, Uhr M, van den Oord EJCG, Van Grootheest G, Völzke H, Weilburg JB, Willemsen G, Zitman FG, Neale B, Daly M, Levinson DF, Sullivan PF (2013). “A mega-analysis of genome-wide association studies for major depressive disorder.” Mol. Psychiatry, 18(4), 497-511. ISSN 1359-4184, 1476-5578, 10.1038/mp.2012.21.
Castro VM, Clements CC, Murphy SN, Gainer VS, Fava M, Weilburg JB, Erb JL, Churchill SE, Kohane IS, Iosifescu DV, Smoller JW, Perlis RH (2013). “QT interval and antidepressant use: a cross sectional study of electronic health records.” BMJ, 346, f288. ISSN 0959-8138, 1756-1833, 10.1136/bmj.f288.2012
Perlis RH, Iosifescu DV, Castro VM, Murphy SN, Gainer VS, Minnier J, Cai T, Goryachev S, Zeng Q, Gallagher PJ, Fava M, Weilburg JB, Churchill SE, Kohane IS, Smoller JW (2012). “Using electronic medical records to enable large-scale studies in psychiatry: treatment resistant depression as a model.” Psychol. Med., 42(1), 41-50. ISSN 0033-2917, 1469-8978, 10.1017/S0033291711000997.
Castro VM, Gallagher PJ, Clements CC, Murphy SN, Gainer VS, Fava M, Weilburg JB, Churchill SE, Kohane IS, Iosifescu DV, Smoller JW, Perlis RH (2012). “Incident user cohort study of risk for gastrointestinal bleed and stroke in individuals with major depressive disorder treated with antidepressants.” BMJ Open, 2(2), e000544. ISSN 2044-6055, 10.1136/bmjopen-2011-000544.
Gallagher PJ, Castro V, Fava M, Weilburg JB, Murphy SN, Gainer VS, Churchill SE, Kohane IS, Iosifescu DV, Smoller JW, Perlis RH (2012). “Antidepressant response in patients with major depression exposed to NSAIDs: a pharmacovigilance study.” Am. J. Psychiatry, 169(10), 1065-1072. ISSN 0002-953X, 1535-7228, 10.1176/appi.ajp.2012.11091325.
Rosenblum JL, Castro VM, Moore CE, Kaplan LM (2012). “Calcium and vitamin D supplementation is associated with decreased abdominal visceral adipose tissue in overweight and obese adults.” Am. J. Clin. Nutr., 95(1), 101-108. ISSN 0002-9165, 1938-3207, 10.3945/ajcn.111.019489.2011
Tatonetti NP, Denny JC, Murphy SN, Fernald GH, Krishnan G, Castro V, Yue P, Tsao PS, Kohane I, Roden DM, Altman RB (2011). “Detecting drug interactions from adverse-event reports: interaction between paroxetine and pravastatin increases blood glucose levels.” Clin. Pharmacol. Ther., 90(1), 133-142. ISSN 0009-9236, 1532-6535, 10.1038/clpt.2011.83.
Greenawalt DM, Dobrin R, Chudin E, Hatoum IJ, Suver C, Beaulaurier J, Zhang B, Castro V, Zhu J, Sieberts SK, Wang S, Molony C, Heymsfield SB, Kemp DM, Reitman ML, Lum PY, Schadt EE, Kaplan LM (2011). “A survey of the genetics of stomach, liver, and adipose gene expression from a morbidly obese cohort.” Genome Res., 21(7), 1008-1016. ISSN 1088-9051, 1549-5469, 10.1101/gr.112821.110.2010
Chen-Tournoux A, Khan AM, Baggish AL, Castro VM, Semigran MJ, McCabe EL, Moukarbel G, Reingold J, Durrani S, Lewis GD, Newton-Cheh C, Scherrer-Crosbie M, Kaplan LM, Wang TJ (2010). “Effect of weight loss after weight loss surgery on plasma N-terminal pro-B-type natriuretic peptide levels.” Am. J. Cardiol., 106(10), 1450-1455. ISSN 0002-9149, 1879-1913, 10.1016/j.amjcard.2010.06.076.
Zhong H, Beaulaurier J, Lum PY, Molony C, Yang X, Macneil DJ, Weingarth DT, Zhang B, Greenawalt D, Dobrin R, Hao K, Woo S, Fabre-Suver C, Qian S, Tota MR, Keller MP, Kendziorski CM, Yandell BS, Castro V, Attie AD, Kaplan LM, Schadt EE (2010). “Liver and adipose expression associated SNPs are enriched for association to type 2 diabetes.” PLoS Genet., 6(5), e1000932. ISSN 1553-7390, 1553-7404, 10.1371/journal.pgen.1000932.