MESA 2015 CHD risk score with CAC

Source: R/chd_10y_mesa_cac.R

Computes 10-year risk for hard coronary heart disease (CHD) event (defined as first occurrence of myocardial infarction (MI), resuscitated cardiac arrest, CHD death, or revascularization with prior or concurrent adjudicated angina). Includes coronary artery calcification score for more precise estimate of risk

chd_10y_mesa_cac(
  race = "white",
  gender = c("male", "female"),
  age,
  totchol = NA,
  hdl = NA,
  lipid_med = NA,
  sbp = NA,
  bp_med = NA,
  smoker = NA,
  diabetes = NA,
  fh_heartattack = NA,
  cac = NA,
  ...
)

Arguments

race

patient race/ethnicity (white, aa, chinese, or hispanic)

gender

patient gender (male, female)

age

patient age (years), risk computed for 45-85 year olds

totchol

Total cholesterol (mg/dL)

hdl

HDL cholesterol (mg/dL)

lipid_med

Patient is on a hyperlipidemic medication (1=Yes, 0=No)

sbp

Systolic blood pressure (mm Hg)

bp_med

Patient is on a blood pressure medication (1=Yes, 0=No)

smoker

Current smoker (1=Yes, 0=No)

diabetes

Diabetes (1=Yes, 0=No)

fh_heartattack

Family history of heart attacks (parents, siblings ,or children) (1=Yes, 0=No)

cac

Coronary artery calcification (Agatston units)

...

Additional predictors can be passed and will be ignored

Value

Estimated 10-Y Risk for hard CAD event (percent)

References

McClelland RL, Jorgensen NW, Budoff M, et al. 10-Year Coronary Heart Disease Risk Prediction Using Coronary Artery Calcium and Traditional Risk Factors: Derivation in the MESA (Multi-Ethnic Study of Atherosclerosis) With Validation in the HNR (Heinz Nixdorf Recall) Study and the DHS (Dallas Heart Study). J Am Coll Cardiol. 2015;66(15):1643-1653. doi:10.1016/j.jacc.2015.08.035

Examples

library(CVrisk)
chd_10y_mesa_cac(
  race = "aa", gender = "male", age = 55,
  totchol = 213, hdl = 50, sbp = 140, lipid_med = 0,
  bp_med = 1, smoker = 0, diabetes = 0, fh_heartattack = 0, cac = 0
)
#> [1] 2.95